INGREDIENT SPOTLIGHT

DE111®

DE111® is a clinically studied strain of Bacillus subtilis—a resilient, spore-forming probiotic developed by ADM. Unlike many standard probiotics, DE111® is shelf-stable, heat-resistant, and survives stomach acid—ensuring it reaches the gut alive and active to deliver targeted benefits.

This hardy strain germinates in the small intestine and goes to work where it matters most—supporting digestion, immunity, and microbiome balance across all ages.

Each serving of QUINIX™ Collagen Fusion+ provides 1.5 Billion CFU of DE111®, the clinically studied dose shown to help promote digestive regularity, strengthen immune defenses, and enhance gut resilience.*

Backed by over 30 safety and efficacy studies, DE111® delivers results you can trust—without refrigeration, synthetic additives, or unnecessary fillers.*

Key Benefits

  • Promotes digestive regularity and stool consistency*
  • Supports nutrient absorption and microbiome balance*
  • Enhances immune response via gut–immune signaling*
  • Clinically shown to survive stomach acid and germinate in the intestines*

Clean & Proven

  • Spore-forming and shelf-stable—no refrigeration required
  • GRAS-affirmed and backed by over 30 human clinical studies
  • Certified non-GMO and allergen-free
  • Manufactured in cGMP-compliant facilities under strict quality controls

How it works

A closer look at what makes this ingredient so effective.

  • Spore-forming shell protects DE111® through digestion for targeted activation in the gut*

  • Supports SCFA production to help nourish gut lining and microbiome balance*

  • Activates immune pathways via gut-associated lymphoid tissue (GALT)*

  • Spore-forming shell protects DE111® through digestion for targeted activation in the gut*

  • Supports SCFA production to help nourish gut lining and microbiome balance*

  • Activates immune pathways via gut-associated lymphoid tissue (GALT)*

Why we use it

Chosen for its clinically studied resilience and ability to colonize the gut, DE111® is a spore-forming probiotic strain of Bacillus subtilis known for supporting digestive balance, nutrient absorption, and immune function. Its natural resistance to heat and stomach acid ensures it arrives alive and active—where it matters most.*

  • Promotes digestive regularity and microbiome balance*
  • Supports nutrient absorption and gut barrier integrity*
  • Enhances immune response through gut–immune axis signaling*
  • GRAS-designated and backed by 30+ published clinical studies*
  • Works in harmony with SNZ 1969® to deliver synergistic probiotic support*

Explore DE111® Benefits

Support daily renewal with clinically backed ingredients—elevating skin, gut, and immune vitality.

A simple daily ritual, meticulously formulated to revitalize your skin, strengthen your gut, and support immune balance—so you can glow from the inside out.

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